I've found five in my RSS feeds that I don't think anyone's mentioned yet and probably aren't too well known to count.
Between Failures updates three days a week in colour but started off in black in white. It's set in a store called Megatainment and follows the goings on of the staff there. There's an interesting bunch of characters and has some very funny lines. Not something for people that like their stories to move fast though. One day in comic time takes a lot of pages.
Milo the Cloud is a cute comic about a talking cloud, a talking balloon and a rather insane bird. It varies between simple one off joke strips and longer story arcs and updates every Monday and Tuesday.
Out at Home is a fantastic comic that follows the Beckett family, headed by Herman, who's a retired baseball player, extremely rich and famous are may as well be on another planet. Updates three times a week.
Zoology is set in a zoo and is mostly about the lives of the various animals there, although the zoo keepers do get some attention too. It jumps between characters a lot and there's a lot of variance between how human their lives are, with some species wearing clothes while others don't and some characters going to school or work while others never leave their pen. One of the animal cast even has a radio show that one of the keepers has listened to on at least one occasion. It updates three times a week in black and white.
Quick Shots is the one I've been reading the longest out of these and is one that I actually did a guest strip for quite a while back. It's a single panel gag strip that has a couple of recurring characters. All the people have rectangular heads and one eye, which I've never asked about but I probably should. It doesn't have a constant update schedule but there's an archive of over 400 of them now, so it's not as if there isn't already a lot of it to read.